Novel poly(ethylene glycol) modified compounds and uses thereof

Details Novel poly(ethylene glycol) modified compounds and uses thereof Novel poly(ethylene glycol) modified compounds and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 1/107 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 14/505 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2525464

The present invention relates to a peptide-based compound comprising a peptide moiety and a poly(ethylene glycol) moiety wherein the poly(ethylene glycol) moiety (preferably linear) has a molecular weight of more than 20 Kdaltons (preferably from 20 to 60 KDaltons). The peptide moiety may be monomeric, dimeric or oligomeric. Such peptide-based compounds may optional include a linker moiety and/or a spacer moiety.

L'invention porte sur un composé peptidique comprenant un fragment de peptide, ainsi qu'un fragment de poly(éthylène glycol) de préférence linéaire présentant un poids moléculaire de plus de 20 Kdaltons (de préférence de 20 à 60 Kdaltons). Le fragment de peptide, qui peut être un monomère, un dimère, ou un oligomère. Lesdits composés peptidiques peuvent facultativement comprendre un fragment de lieur et/ou d'espaceur.

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