C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/78 (2006.01) A61K 31/16 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) C07C 233/38 (2006.01) C07C 233/62 (2006.01) C07C 311/11 (2006.01) C07C 311/14 (2006.01) C07C 311/18 (2006.01)
Patent
CA 2410935
Novel "bispolyamine" inhibitor compounds of polyamine transport are disclosed. These compounds are useful pharmaceutical agents for treating diseases where it is desired to inhibit polyamine transport or other polyamine binding proteins, for example cancer and post-angioplasty injury. These compounds display desirable activities both for diagnostic and research assays and therapy.
L'invention concerne des nouveaux composés inhibiteurs à la <= bispolyamine >=, inhibant le transport de la polyamine. Lesdits composés sont des agents pharmaceutiques utiles pour le traitement de maladies pour lesquelles il est souhaitable d'inhiber le transport de la polyamine ou d'autres protéines de liaison de la polyamine, par exemple le cancer et les lésions post-angioplastie. Lesdits composés ont les activités voulues à la fois pour les essais diagnostiques, de recherche et thérapeutiques.
Bergstrom Donald E.
Burns Mark R.
O'day Christine L.
Vermeulin Nicolaas M. J.
Webb Heather K.
Heenan Blaikie Llp
Mediquest Therapeutics Inc.
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