C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2217785
The invention relates to 13-hydroxy-tylosine derivatives, novel semisynthetic antibiotics from the class of macrolides, and to a process for the preparation thereof. According to the present invention by a reductive opening of the oxirane ring of tylosine 13-hydroxy compounds are obtained, which are then subjected to a hydrogenation of the double bond and then 13-hydroxy dihydro or tetrahydro compounds are subjected to an oximation reaction or 13-hydroxy oximes are subjected to the hydrogenation of the double bond.
L'invention porte sur des dérivés de 13-hydroxytylosine, nouveaux antibiotiques semi-synthétiques de la catégorie des macrolides, et sur leur préparation. Selon l'invention, l'ouverture par réduction du cycle oxirane de la tylosine donne des composés 13-hydroxylés, qui sont ensuite soumis à une hydrogénation de la double liaison; les composés 13-hydroxy-dihydro ou -tétrahydro sont ensuite soumis à une réaction d'oximation, ou la double liaison des 13-hydroxyoximes est hydrogénée.
Lopotar Nevenka
Narandja Amalija
Borden Ladner Gervais Llp
Dion Icko Drustvo Pliva Farmaceutska Kemijska Prehrambena I. Kozmeticka Industrija
LandOfFree
Novel polyhydro derivatives of tylosine and process for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel polyhydro derivatives of tylosine and process for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel polyhydro derivatives of tylosine and process for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1874841