Novel polymorphic forms of perindopril (l)-arginine and...

Details Novel polymorphic forms of perindopril (l)-arginine and... Novel polymorphic forms of perindopril (l)-arginine and...

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2729604

The present invention relates to novel and stable polymorphic forms of Perindopril (L)- Arginine designated as Form .gamma. and amorphous form and processes for their preparation. The present invention also provides the novel polymorph Form .gamma. with greater stability to heat and humidity and can be prepared on large scale by an efficient, economic and reproducible process.

L'invention concerne des formes polymorphes nouvelles et stables de Perindopril (L)- arginine désignées par forme ? et forme amorphe, et des procédés de préparation de celles-ci. La présente invention fournit également la nouvelle forme ? polymorphe présentant une plus grande stabilité à la chaleur et à l'humidité et qui peut être préparée à grande échelle au moyen d'un processus efficace, économique et reproductible.

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