Novel polymorphs and processes for their preparation

C - Chemistry – Metallurgy – 07 – D

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C07D 403/06 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2715657

The present invention relates to novel polymorph forms III and IV of sunitinib malate, pharmaceutical compositions comprising the novel polymorphs and the use of the pharmaceutical compositions. The present invention further relates to processes for the preparation of polymorph form I, III and IV of sunitinib malate.

L'invention porte sur de nouvelles formes polymorphes III et IV du malate de sunitinib, sur des compositions pharmaceutiques comprenant les nouveaux polymorphes et sur l'utilisation desdites compositions pharmaceutiques. L'invention se rapporte en outre à des procédés de préparation des formes polymorphes I, III et IV du malate de sunitinib.

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