Novel polymorphs of the potassium salt of atorvastatin

Details Novel polymorphs of the potassium salt of atorvastatin Novel polymorphs of the potassium salt of atorvastatin

C - Chemistry, Metallurgy

07

D

C07D 207/40 (2006.01)

Patent

CA 2577848

Novel polymorphs Forms I, II and III of the potassium salt of Atorvastatin, (.beta.R,.delta.R)-2-(p~fluorophenyl)-( .beta.,.delta.-dihydroxy-5-isopropyl-3- phenyl-4-(phenylcarbamoyl)pyrrole-l -heptanoic acid, are obtained directly by precipitation of the potassium salt of Atorvastatin with ethanol (polymorph I), with 1-propanol (polymorph II) and by recrystallisation of polymorph I from 2-~propanol (polymorph III).

La présente invention concerne de nouvelles formes polymorphes I, II et III du sel de potassium de l~Atorvastatine, l~acide (.beta.R,.delta.R)-2-(p-fluorophényl)-( .beta.,.delta.-dihydroxy-5-isopropyl-3-phényl-4-(phénylcarbamoyl)pyrrole-1-heptanoïque, obtenues directement par précipitation du sel de potassium de l~Atorvastatine par de l~éthanol (polymorphe I), par du 1-propanol (polymorphe II) et par recristallisation du polymorphe I dans du 2-propanol (polymorphe III).

Affiliated with

Also associated with

Rating

Novel polymorphs of the potassium salt of atorvastatin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel polymorphs of the potassium salt of atorvastatin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel polymorphs of the potassium salt of atorvastatin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1720418