C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 1/14 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2491083
The present invention provides a purified nucleic acid encoding a putative transmembrane receptor polypeptide comprising at its N-terminus leucine rich repeats and at least an immunoglobulin domain. S30-21616/DEGA polypeptide of the present invention, analogs of said polypeptide, vectors and host cells that embody the polynucleotides, bio-immunopharmaceutical compositions and diagnostic reagents comprising the polypeptides, analogs and derivatives and methods for making and utilizing the polypeptides are disclosed.
La présente invention a trait à un acide nucléique purifié codant pour un polypeptide récepteur transmembranaire présumé comportant au niveau de son N-terminal des séquences nucléotidiques répétées riches en leucine et au moins un domaine d'immunoglobuline. L'invention a trait également au polypeptide S30-21616/DEGA, des analogues dudit polypeptide, des vecteurs et des cellules hôtes comprenant les polynucléotides, des compositions biologiques immunopharmaceutiques et des réactifs de diagnostic comprenant les polypeptides, leurs analogues et dérivés et des procédés de fabrication et d'utilisation des polypeptides.
Gowling Lafleur Henderson Llp
Imclone Llc
Imclone Systems Incorporated
Pereira Daniel S.
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