Novel polynucleotides and polypeptides encoded thereby

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2386346

The present invention provides novel polypeptides, termed PTMAX polypeptides, as well as polynucleotides encoding PTMAX polypeptides and antibodies that immunospecifically bind to PTMAX or a derivative, variant, mutant, or fragment of the PTMAX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the PTMAX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne des nouveaux polypeptides, appelés polypeptides PTMAX, ainsi que des polynucléotides codant ces polypeptides PTMAX et des anticorps se liant de manière immunospécifique à PTMAX, ou tout dérivé, variant, mutant ou fragment de ces polypeptides, de ces polynucléotides ou de ces anticorps PTMAX. Par ailleurs, l'invention concerne des procédés faisant intervenir ces polypeptides, ces polynucléotides et ces anticorps PTMAX dans la détection et le traitement d'un large éventail d'états pathologiques et dans d'autres applications.

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