Novel polynucleotides and polypeptides encoded thereby

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2375424

The present invention provides isolated NOVX polypeptides, as well as polynucleotides encoding them and antibodies that immunospecifically bind to NOVX or any derivative, variant, mutant, or fragment of NOVX polypeptides, polynucleotides or antibodies. The invention additionally provides methods in which the NOVX polypeptides, polynucleotides, and antibodies are used in detection and treatment of a broad range of pathological states, as well as other uses.

L'invention concerne de polypeptides NOVX isolés, ainsi que des polynucléotides codant pour ceux-ci, et des anticorps qui se lient de manière immunospécifique à NOVX ou à un dérivé, un variant, un mutant quelconques, ou à un fragment de polypeptides, de polynucléotides ou d'anticorps NOVX. L'invention concerne également des techniques dans lesquelles on utilise les polypeptides, les polynucléotides, et les anticorps NOVX pour détecter et traiter un large spectre d'états pathologiques, ainsi que d'autres utilisations.

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