C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) A01K 67/027 (2006.01) A61K 38/00 (2006.01) C07K 14/47 (2006.01) C07K 14/715 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2382123
Disclosed are four novel human nucleic acid sequences expressed in activated T- lymphocytes. Also provided are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to a polypeptide of the invention, or any derivative, variant, mutant or fragment of the polypeptide, polynucleotide or antibody. The invention further provides therapeutic, diagnostic and research methods for treating and diagnosing disorders related to these novel human T-lymphocyte proteins.
L'invention concerne quatre nouvelles séquences humaines d'acide nucléique exprimées dans les lymphocytes T activés. L'invention concerne également des polypeptides codés par ces séquences d'acide nucléique, et des anticorps qui se lient d'une manière immunospécifique à un tel polypeptide, ou un quelconque dérivé, variant, mutant ou fragment du polypeptide, du polynucléotide ou de l'anticorps. L'invention concerne en outre des méthodes thérapeutiques, diagnostiques et de recherche permettant de traiter et de diagnostiquer des troubles associés à ces nouvelles protéines des lymphocytes T humains.
Browning Jeffrey L.
Carulli John
Green Cynthia D.
Hsu Andro
Peyman John A.
Biogen Inc.
Curagen Corporation
Everitt Peter R.
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