Novel polypeptide

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/563 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2374341

A novel secretory protein or its salt; a process for producing this protein; drugs containing this protein; an antibody against this protein; a method/kit for screening a compound or its salt which promotes or inhibits the activity of the above protein, and the like. The above protein is usable in remedies and preventives for various diseases such as cancer, immune diseases, lung function disorder, liver function disorder, infectious diseases and gastrointestinal disorder. The above antibody is usable in quantitating the above protein in test samples, etc. Further, the above protein is useful as a reagent for screening a compound which promotes or inhibits the activity of this protein.

Cette invention concerne une nouvelle protéine sécrétrice ou son sel, un procédé de production de celle-ci, des médicaments la renfermant, un anticorps contre cette protéine ainsi qu'une méthode/un nécessaire permettant de procéder au criblage d'un composé ou de son sel favorisant ou inhibant l'activité de la protéine susmentionnée et analogue. Cette protéine est utilisable avec des remèdes et des substances à vocation prophylactique, utilisés dans le cadre de diverses affections, notamment, des cancers, des maladies immunitaires, des troubles pulmonaires et hépatiques, des maladies infectieuses ainsi que des troubles gastro-intestinaux. Il est possible d'utiliser l'anticorps susmentionné pour quantifier la protéine susmentionnée dans des échantillons d'essai, etc. Cette protéine est, en outre, des plus utile comme réactif pour le criblage d'un composé favorisant ou inhibant l'activité de ladite protéine.

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