C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2460468
It is intended to provide a novel polypeptide, a receptor, DNA thereof, etc. More specifically, a polypeptide capable of binding to a protein represented by SEQ ID NO:1 or 3, its amide, its ester or its salt; a polynucleotide encoding the above polypeptide; an antisense polynucleotide of the above polypeptide or its antibody; a method of screening a preventive/remedy for cancer, obesity and the like using the same, etc. The polypeptide, receptor, polynucleotide, antisense polynucleotide, antibody, etc. as described above are useful as preventives/remedies for cancer, obesity and the like. Moreover, they are useful in screening preventives/remedies for cancer, obesity and the like.
L'invention concerne un nouveau polypeptide, un récepteur, un ADN de celui-ci, etc. L'invention concerne plus précisément un polypeptide pouvant se lier à une protéine représentée par SEQ ID NO:1 ou 3, son amide, son ester ou son sel, un polynucléotide codant ce polypeptide, un polynucléotide antisens de ce polypeptide ou son anticorps, un procédé de criblage d'un médicament préventif/remède contre le cancer, l'obésité et analogue au moyen de ceux-ci, etc. Le polypeptide, le récepteur, le polynucléotide, le polynucléotide antisens, l'anticorps, etc., mentionnés ci-dessus sont utiles en tant que médicaments préventifs/remèdes contre le cancer, l'obésité et analogue. Ils sont en outre utiles dans le criblage de médicaments préventifs/remèdes contre le cancer, l'obésité et analogue.
Hayashi Kozo
Kitada Chieko
Matsumoto Hirokazu
Miya Hiroyuki
Mori Masaaki
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
Takeda Pharmaceutical Company Limited
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