Novel polypeptides and nucleic acids encoding same

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 38/17 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 9/50 (2006.01) C12N 15/56 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2391908

The present invention provides novel isolated SERX polynucleotides and polypeptides encoded by the SERX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SERX polypeptide or any derivative, variant, mutant or fragment of the SERX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SERX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

L'invention concerne de nouveaux polynucléotides SERX isolés et des polypeptides codés par ces polynucléotides SERX. L'invention concerne également des anticorps qui lient de manière immunospécifique à un polypeptide SERX ou tout dérivé, variant, mutant ou fragment de ce polypeptide, polynucléotide ou anticorps SERX. La présente invention fait également état de procédés dans lesquels les polypeptides, polynucléotides et anticorps SERX sont utilisés afin de détecter et traiter une large gamme d'états pathologiques ainsi que d'autres utilisations.

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