C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2425302
Disclosed herein are novel human nucleic acid sequences that have homology to thymosin, ephrin A receptors, proteoglycans and fibromodulin. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving these novel nucleic acids and proteins.
Cette invention concerne des séquences d'acides nucléiques humains présentant une homologie avec la thymosine, les récepteurs de l'éphrine A, les protéoglycanes et la fibromoduline. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques et des anticorps qui se lient de manière immunospécifique avec le polypeptide, ainsi que des dérivés, variants, mutants ou fragments du polypeptide, polynucléotide ou anticorps susmentionnés. De plus, l'invention concerne des méthodes thérapeutiques, diagnostiques et de recherche pour le diagnostic, le traitement et la prévention de troubles en rapport avec ces nouveaux acides nucléiques et protéines.
Bandaru Raj
Prayaga Sudhirdas K.
Taupier Raymond J.
Curagen Corporation
Everitt Peter R.
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