C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2067901
A novel polypeptide sequence having the formula 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 A1-A2-Cys-A2-A3-A3-Cys-A2-A3-Gly-A2-Cys-A2-A3-A3-Cys-A4-A5 in which A1 is a hydrogen or at least one and no more than two amino acids selected from the group consisting of lysine and arginine, A2 is a tyrosine, phenylalanine or tryptophan residue, A3 is an arginine or lysine residue, A4 is at least one and no more than two amino acids selected from the group consisting of lysine and arginine, and A5 is an -OH or an NH2, is described. The polypeptide may be used in a pharmaceutical composition as an antimicrobial or antiviral agent, specifically as an anti-HIV agent.
Fujii Nobutaka
Matsumoto Akiyoshi
Waki Michinori
Yamamoto Naoki
Osler Hoskin & Harcourt Llp
Seikagaku Kogyo Kabushiki Kaisha
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