C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01K 67/027 (2006.01) A61K 31/713 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/18 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2511564
The present invention discloses open reading frames (ORFs) in human genome encoding for novel Preadipocyte factor-1-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
L'invention concerne des cadres de lecture ouverts (ORF) du génome humain codant pour des nouveaux polypeptides de type facteur 1 des préadipocytes, et des réactifs associés à ceux-ci, comprenant des variants, de mutants et des fragments desdits polypeptides ainsi que des ligands et des antagonistes dirigés contre ces polypeptides. L'invention concerne en outre des procédés permettant d'identifier et de produire ces molécules, de préparer des compositions pharmaceutiques les contenant, et de les utiliser pour le diagnostic, la prévention et le traitement de maladies.
Bienkowska Jadwiga
Mcallister Gregg
Applied Research Systems Ars Holding N.v.
Borden Ladner Gervais Llp
Laboratoires Serono S.a.
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