C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61P 25/18 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2427502
The present invention relates to novels primers useful for identifying and screening non- sense mutation with codon TGG coding for amino acid tryptophan substituted with TAG a non-sense colon at nucleotide No. 825 in exon 2 of synaptogy~n 1 gene of chromosome 22q11-13 thereby detecting pre-disposition to schizophrenia in a subset of patients and a method thereof.
La présente invention concerne de nouvelles amorces utiles pour identifier et cribler une mutation non-sens avec un codon TGG codant l'acide aminé tryptophane substitué avec un TAG, codon non-sens situé au niveau du nucléotide No. 825 dans l'exon 2 du gène de synaptogyrine 1 du chromosome 22q11-13, ce qui permet ainsi de détecter une prédisposition à la schizophrénie chez un sous-ensemble de patients. L'invention concerne également une méthode associée.
Brahmachari Samir Kumar
Chitra Chauhan
Jain S.
Ranjana Verma
Salim Q.
Council Of Scientific And Industrial Research
R. William Wray & Associates
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