C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/34 (2006.01) A61K 31/506 (2006.01) A61P 25/28 (2006.01) C07D 209/34 (2006.01) C07D 403/06 (2006.01)
Patent
CA 2729253
The present invention relates to novel intermediates and further to the use of said intermediates in processes for the preparation of indolinone derivatives, in particular 3- pyrrole substituted 2- indolinones having amide moieties on the pyrrole ring Such compounds are useful m die treatment of abnormal cell growth, such as cancer, in mammals.
L'invention porte sur de nouveaux intermédiaires et sur leur utilisation dans la préparation de dérivés d'indolinone, et en particulier de 2-indolinones à substitution 3- pyrrole présentant des fragments d'amide sur le cycle pyrrole. De tels composés sont utiles dans le traitement des croissances cellulaires anormales telles que le cancer des mammifères.
Bansode Prakash
Choudhari Bharati
Gaitonde Abhay
Phadtare Sunanda
Generics [uk] Limited
Osler Hoskin & Harcourt Llp
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