A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/513 (2006.01)
Patent
CA 2629912
The present invention provides for a novel process of making 6-carboxylic acid derivatives of pyrido[2,3-<d]pyrimidin-7-one's, as well as a novel process for making 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-l- (hydroxymethyl)ethyl]-amino}pyrido[2,3-d]pyrimidin-7(8H)-one, and salts thereof.
La présente invention concerne un nouveau procédé pour préparer des dérivés acide 6-carboxylique de la pyrido[2,3-d]pyrimidin-7-one, ainsi qu~un nouveau procédé pour préparer la 8-(2,6-difluorophényl)-4-(4-fluoro-2-méthylphényl)-2-{[2-hydroxy-1-(hydroxyméthyl)éthyl]-amino}pyrido[2,3-d]pyrimidin-7(8H)-one et des sels de celle-ci.
Abu Khalil As'ad
Appleby John Robert George
Blatcher Philip
Diederich Ann M.
Humphries Lesley Anne
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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