C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/08 (2006.01) C07K 1/00 (2006.01) C07K 1/02 (2006.01) C07K 1/04 (2006.01) C07K 1/10 (2006.01) C07K 5/10 (2006.01)
Patent
CA 2458084
A new hybrid solid phase-liquid phase method of Octreotide synthesis is invented. This method comprises liquid phase condensation of at least two peptide blocks, from which at least one is synthesized by solid-phase method. Every such block should contain two or more amino acid residues. The method of invention combines the time and labor effectiveness of the solid-phase method with relative cheapness and easiness of purification of the product, characteristic for the liquid-phase method.
Avrutov Ilya
Houldsworth Stephen
Iarov Alexei
Lazarowych Natalie
Borden Ladner Gervais Llp
Dalton Chemical Laboratories Inc.
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