Novel process for preparing n-acetyl(l)-4-cyanophenylalanine...

Details Novel process for preparing n-acetyl(l)-4-cyanophenylalanine... Novel process for preparing n-acetyl(l)-4-cyanophenylalanine...

C - Chemistry, Metallurgy

12

P

C12P 13/04 (2006.01) C07K 5/09 (2006.01) C12P 13/02 (2006.01) C12P 21/02 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2241210

The present invention is related to a novel process for preparing N-acetyl-(L)- 4-cyanophenylalanine by resolving the racemic compound N-acetyl-(D, L)-4- cyanophenylalanine ethyl ester, and a novel process to prepare a stereoisomer of Ac-(L)-pAph-Chg-PalMe(3)-NH2 by using the intermediate N-acetyl-(L)-4- cyanophenylalanine.

La présente invention concerne un procédé nouveau de préparation de N-acétyl(L)-4-cyanophénylalanine par résolution du composé racémique N-acétyl-(D, L)-4-cyanophénylalanine éthyle ester et un procédé nouveau de préparation d'un stéréoisomère d'Ac-(L)-pAph-Chg-PalMe(3)-NH¿2? grâce à l'utilisation de la N-acétyl-(L)-4-cyanophénylalanine intermédiaire.

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