Novel process for synthesis of heteroaryl-substituted urea...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/40 (2006.01) C07D 401/12 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2374737

Disclosed are novel processes and novel intermediate compounds for preparing aryl- and heteroaryl-substituted urea compounds of formula (I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in pharmaceutic compositions for treating diseases or patho-logical conditions involving inflammation such as chronic inflammatory diseases.

L'invention concerne de nouveaux procédés et de nouveaux composés intermédiaires permettant de préparer des composés d'urée à substitution aryle et à substitution hétéroaryle de formule (I), dans laquelle Ar1, Ar2, L, Q, et X sont tels que définis dans la description. Les composés ainsi élaborés peuvent être utilisés dans des compositions pharmaceutiques destinées à traiter des maladies ou des pathologies qui se manifestent par une inflammation, par exemple les maladies inflammatoires chroniques.

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