Novel process for the preparation of cetrorelix lyophilisate

A - Human Necessities – 61 – K

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Details

A61K 38/08 (2006.01) A61K 9/14 (2006.01) A61K 9/19 (2006.01) A61K 38/04 (2006.01) A61K 38/09 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2115943

A novel lyophilisate and method of preparation as well as the use of the lyophilisate to treat female infertility and for gonad protection. A lyophilisate of a peptide with 3 - 15 amino acids and optionally one or several bulking agents is prepared by dissolving 1 part by weight of peptide in 100 - 10,000 parts by weight of acetic acid and then transferring to water, the solution so obtained being lyophilized. Cetrorelix is preferred as the peptide.

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