Novel process for the preparation of crystalline venlafaxine...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 217/74 (2006.01)

Patent

CA 2550252

The claimed invention provides a novel methods of preparing Venlafaxine hydrochloride Form B. The process comprises the steps of dissolving any form of Venlafaxine hydrochloride either in water or in mixture of water and suitable solvent, azeotropically removing the water from said solution. It also comprises the steps of suspending any form of Venlafaxine Hydrochloride in suitable solvent, seeding Venlafaxine Hydrochloride Form B to said suspension and isolating crystalline Venlafaxine hydrochloride Form B.

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