Novel process for the preparation of scopine esters

C - Chemistry – Metallurgy – 07 – D

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C07D 451/10 (2006.01)

Patent

CA 2710523

The present invention relates to novel processes for the preparation of scopine esters and their quaternary salts. In particular, the present invention relates to a process for the preparation of tiotropium bromide, pharmaceutical compositions comprising tiotropium bromide and the use of such compositions in the treatment of respiratory disorders.

La présente invention porte sur de nouveaux procédés de préparation d'esters de scopine et de leurs sels quaternaires. En particulier, la présente invention porte sur un procédé de préparation de bromure de tiotropium, sur des compositions pharmaceutiques comprenant du bromure de tiotropium et sur l'utilisation de ces compositions dans le traitement de troubles respiratoires.

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