C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/185 (2006.01) C07C 57/32 (2006.01)
Patent
CA 2538995
An improved process for the preparation of 5-(4- fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro- pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3- carboxylic acid phenylamide Image by a novel synthesis is described where methyl cyanoacetate is converted in eight operations or fewer to the desired product, as well as other valuable intermediates used in the process.
Butler Donald Eugene
Dejong Randall Lee
Nelson Jade Douglas
Pamment Michael Gerard
Stuk Timothy Lee
Smart & Biggar
Warner-Lambert Company Llc
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