Novel prostamides for the treatment of glaucoma and related...

C - Chemistry – Metallurgy – 07 – C

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C07C 405/00 (2006.01) A61K 31/557 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2546013

Disclosed herein are compositions comprising an amide related to a prostaglandin and an amine wherein the amine is selected from the group consisting of epinephrine, dopamine, serotonin, and analogs or prodrugs thereof. Also disclosed are certain chemical compounds, pharmaceutical compositions, and methods of treating glaucoma (Formula A).

L'invention concerne des compositions comprenant un amide associé à une prostaglandine et un amine sélectionné dans le groupe constitué par épinéphrine, dopamine, sérotonine et des analogues et de promédicaments de celles-ci. L'invention concerne également certains composé chimiques, des compositions pharmaceutiques et des méthodes permettant de traiter un glaucome (Formula A).

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