C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 35/76 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) C07K 16/40 (2006.01) C12N 9/64 (2006.01) C12Q 1/37 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2420275
It is intended to provide a novel diagnostic means and medicinal compositions by finding out and providing a novel neurolysin-like substance in humans, analyzing the function, localization, etc. of the novel neurolysin-like substance in humans, clarifying the role of this substance in vivo and thus controlling its function. A novel neurolysin-like substance having an activity of degrading a synthetic substrate Mcc-Pro-Leu-Gly-Pro-D-Lys(DNP)-OH is found out.
La présente invention concerne un nouveau moyen diagnostic et des compositions médicinales obtenues suite à la découverte et à l'obtention d'une substance de type neurolysine chez des humains, à l'analyse de la fonction, de l'emplacement, etc. de cette nouvelle substance de type neurolysine chez des humains, à la précision du rôle de cette substance in vivo et à la régulation de sa fonction. L'invention concerne également une nouvelle substance de type neurolysine possédant une activité de dégradation d'un substrat synthétique Mcc-Pro-Leu-Gly-Pro-D-Lys(DNP)-OH.
Arai Yasuko
Inoue Tatsuya
Saeki Yoshiyuki
Wada Naoya
Yokota Hiroshi
Daiichi Pharmaceutical Co. Ltd.
Moffat & Co.
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