Novel protein and dna thereof

Details Novel protein and dna thereof Novel protein and dna thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/46 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/48 (2006.01) C12N 9/64 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2341327

A novel protein belonging to the ADAM family, its peptide fragment or salts thereof; a DNA encoding this protein; a recombinant vector containing this DNA; a transformant; a process for producing the above protein; drugs containing the protein or DNA; an antibody against the protein; a method/kit for screening a compound capable of promoting or inhibiting the protease activity or the extracellular matrix digesting enzyme activity of the above protein; compounds obtained by this screening; drugs containing these compounds, etc.

Cette invention se rapporte à une nouvelle protéine appartenant à la famille ADAM, à son fragment peptidique ou à des sels de celui-ci; à un ADN codant cette protéine; à un vecteur de recombinaison contenant cet ADN; à un transformant; à un procédé servant à produire cette protéine; à des médicaments contenant cette protéine ou cet ADN; à un anticorps contre cette protéine; à un procédé/kit servant à cribler un composé capable de favoriser ou d'inhiber l'activité de protéase de cette protéine ou son activité d'enzyme de digestion de la matrice extracellulaire; à des composés obtenus par cette technique de criblage; et à des médicaments contenant ces composés, notamment.

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