Novel protein and dna thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/711 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 31/00 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2391403

A novel protein and a DNA encoding the same which are usable, for example, as remedies/preventives for diseases such as infectious diseases. This protein is also useful as a reagent for screening a compound or its salt capable of promoting or inhibiting the activity of this protein. A compound or its salt inhibiting the activity of the above protein and a neutralization antibody inhibiting the activity of the above protein are usable as remedies/preventives for diseases such as bronchial asthma and chronic obstructive pulmonary disease.

La présente invention concerne une nouvelle protéine et l'ADN codant pour celle-ci s'utilisant par exemple comme agents thérapeutiques/prophylactiques pour certaines maladies, notamment les maladies infectieuses. On utilise également cette protéine comme réactif pour cribler un composant ou son sel capable de stimuler ou d'inhiber l'activité de cette protéine. Par ailleurs, on peut utiliser un composé ou son sel inhibant l'activité de cette protéine et un anticorps de neutralisation inhibant l'activité de cette protéine comme agents thérapeutiques/prophylactiques de certaines maladies, notamment de l'asthme bronchique et des broncho-pneumopathies chroniques obstructives.

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