Novel protein and its use

Details Novel protein and its use Novel protein and its use

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) C07K 7/06 (2006.01) C07K 16/18 (2006.01) C12N 5/18 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2364941

Novel secretory proteins, peptide segments constituting the same, or salts thereof; a process for the preparation of the proteins; medicines containing the proteins; antibodies against the proteins; methods and kits for the screening for compounds which promote or hinder the activities of the proteins or salts of the compounds; compounds obtained by the screening; medicines containing these compounds; and so on. The proteins and the peptide segments are usable as regenerators applicable after the extirpation of sick tissues, diagnostic agents for cancers, or the like. The antibodies are useful in determining the contents of the proteins in test solutions. The proteins are useful as reagents for the screening for compounds which promote or hinder the activities of the proteins.

La présente invention concerne, d'une part de nouvelles protéines sécrétoires, des segments peptidiques constitutifs de ces protéines, ou certains de leurs sels, et d'autre part un procédé de préparation des ces protéines. L'invention concerne en outre des médicaments contenant ces protéines, des anticorps dirigés contre ces protéines, des procédés et des nécessaires de recherche systématique de composés favorisant les activités des protéines ou des sels des composés ou s'y opposant. L'invention concerne enfin notamment des composés obtenus par cette recherche systématique et des médicaments contenant ces composés. Les protéines et les segments peptidiques de l'invention conviennent notamment comme régénérateurs s'appliquant après ablation de tissus atteints, et comme agents de diagnostic de cancers. Les anticorps conviennent à la détermination du contenu des protéines dans les solutions de test. Ces protéines conviennent comme réactifs dans la recherche systématique de composés favorisant les activités des protéines ou s'y opposant.

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