Novel protein tyrosine kinase, jak3

Details Novel protein tyrosine kinase, jak3 Novel protein tyrosine kinase, jak3

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/40 (2006.01) C12N 5/08 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2207626

A novel protein tyrosine kinase, JAK3, and a polynucleotide sequence encoding JAK3 polypeptide are disclosed herein. JAK3 is a new member of the JAK family of protein tyrosine kinases which are important in regulation of cellular proliferation and differentiation. Also disclosed are therapeutic methods utilizing JAK3 polypeptide and polynucleotide sequences.

Cette invention concerne une nouvelle tyrosine kinase protéique, JAK3, ainsi qu'une séquence polynucléotidique codant le polypeptide JAK3. Cette JAK3 est un nouveau membre de la famille JAK des tyrosines kinases protéiques qui jouent un rôle important dans la régulation de la prolifération et de la différenciation cellulaires. Sont également décrits des procédés thérapeutiques dans lesquels on emploie ledit polypeptide JAK3 et lesdites séquences polynucléotidiques.

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