Novel proteinase inhibitor and gene encoding the inhibitor

Details Novel proteinase inhibitor and gene encoding the inhibitor Novel proteinase inhibitor and gene encoding the inhibitor

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/81 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2208202

The present invention relates to a novel proteinase inhibitor useful as a medicine or pesticides and a gene coding for the inhibitor. A proteinase inhibitor (Kexstatin) having inhibitory activity against Kex2 proteinase family enzymes and having a molecular weight of 11,500; a gene coding for Kexstatin; and a method for producing Kexstatin using a microorganism belonging to the genus Streptomyces or transformed with Kexstatin gene are disclosed.

La présente invention concerne un nouvel inhibiteur de protéinase utile comme médicament ou pesticide et un gène codant cet inhibiteur, un inhibiteur de protéinase (kexstatine) ayant une activité inhibitrice sur les enzymes de la famille des protéinases Kex2 et ayant un poids moléculaire de 11 500, un gène codant la kexstatine ainsi qu'une méthode pour produire la Kexstatine à l'aide d'un microorganisme appartenant au genre Streptomyces ou transformé avec le gène de la kexstatine.

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