Novel proteins and nucleic acids encoding same

Details Novel proteins and nucleic acids encoding same Novel proteins and nucleic acids encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/16 (2006.01) A61K 38/22 (2006.01) A61K 38/28 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2407494

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acide nucléique qui codent des polypeptides du récepteur couplé à la protéine G, des polypeptides codés par ces séquences d'acide nucléique, des anticorps qui se lient de manière immunospécifique au polypeptide ainsi que des dérivés, des variants, des mutants ou des fragments dudit polypeptide, dudit polynucléotide ou dudit anticorps. L'invention concerne également des procédés de thérapie, de diagnostic et de prévention des maladies associées à un de ces nouveaux acides nucléiques humains ou à une de ces nouvelles protéines humaines..

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