Novel pseudoerythromycin derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2386828

The present invention is to obtain novel anti-inflammatory agents having decreased antibacterial activity and increased anti-inflammatory action, and is psedoerythromycin derivatives represented by the following general formula (I], (see formula I) wherein R1 and R2 are same or different and each represents H, alkyl, alkynyl, acyl or sulfonyl, in which these groups may optionally have substituents, and Me indicates methyl.

L'invention concerne des dérivés de pseudoérythromycine de formule générale (I), qui représentent de nouveaux agents anti-inflammatoires présentant des activités anti-bactériennes réduites et des activités anti-inflammatoires accrues, formule dans laquelle R1 et R2 représentent chacun indépendamment H, alkyle, alcynyle, acyle ou sulfonyle, à condition que ces groupes puissent chacun être substitués, et Me représente méthyle.

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