C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2624829
In its many embodiments, the present invention provides a novel class of pyrazolo[1 ,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Dans ses différents modes de réalisation, la présente invention a trait à une nouvelle classe de composés pyrazolo[1,5-a]pyrimidine en tant qu'inhibiteurs des kinases dépendantes des cyclines, à des procédés de préparation de tels composés, à des compositions pharmaceutiques contenant un ou plusieurs de ces composés, à la préparation de formulations pharmaceutiques comprenant un ou plusieurs de ces composés, et à des procédés de traitement, de prévention, d'inhibition, ou d'amélioration d'une ou de plusieurs maladies associées aux kinases dépendantes des cyclines mettant en oeuvre ces composés ou compositions pharmaceutiques.
Dwyer Michael P.
Guzi Timothy J.
Keertikar Kartik M.
Labroli Marc
Paruch Kamil
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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