C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2665127
In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Dans ses différents modes de réalisation, l'invention concerne une classe de composés de pyrazolo[1,5-a]pyrimidine servant d'inhibiteurs de kinases cycline-dépendantes (CDK). L'invention concerne des procédés de préparation de tels composés, des compositions pharmaceutiques contenant au moins un de ces composés, des procédés de préparation de formulations pharmaceutiques comprenant au moins un de ces composés, et des procédés de traitement, de prévention, d'inhibition, ou d'amélioration d'au moins une maladie associée aux CDK, faisant appel à de tels composés ou à de telles compositions pharmaceutiques.
Dwyer Michael P.
Guzi Timothy J.
Keertikar Kartik M.
Labroli Marc
Paruch Kamil
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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