C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61P 3/10 (2006.01) C07D 213/73 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2474578
The present invention relates to compounds of formula (I) (see formula I) wherein R1, R2, R3, R4 and X are as defined in the description, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
L'invention concerne des composés représentés par la formule (I). Dans cette formule, R<1>, R<2>, R<3>, R<4 >et X sont tels que définis dans la description et les revendications. L'invention concerne également des sels de ces composés acceptables sur le plan pharmaceutique. Les composés de l'invention sont utiles dans le traitement et/ou la prévention de maladies associées au DPP-IV, notamment le diabète, et plus particulièrement, le diabète non insulino-dépendant, et d'une altération de la tolérance au glucose.
Boehringer Markus
Loeffler Bernd Michael
Peters Jens-Uwe
Steger Matthias
Weiss Peter
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
LandOfFree
Novel pyridin- and pyrimidin-derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel pyridin- and pyrimidin-derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel pyridin- and pyrimidin-derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1664704