Novel pyridine derivatives, a process for their preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/052 (2006.01)

Patent

CA 2552207

This invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.

La présente invention a trait à de nouveaux dérivés de pyridine présentant un effet d'inhibition sur la production de cytokines, qui sont impliquées dans des réactions inflammatoires, indiquant ainsi leur utilité comme agents thérapeutiques pour le traitement de maladies associées à l'inflammation, immunitaires, l'inflammation chronique ainsi qu'un agent présentant un effet anti-inflammatoire et analgésique. L'invention a également trait à un procédé pour la fabrication des dérivés et à une composition pharmaceutiques contenant lesdits dérivés.

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