C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/04 (2006.01) A61K 31/44 (2006.01) C07D 209/12 (2006.01) C07D 213/30 (2006.01) C07D 213/64 (2006.01) C07D 213/85 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2284597
A compound of formula (I) wherein; X is O, S or CH2; R1 and R2 are independently hydrogen, C1-6 alkyl or C3-6 cycloalkyl or R1 and R2 together with the carbon atom to which they are attached form a C3-6cycloalkyl group. The compounds of the invention are indicated for use in the treatment or prevention of allergic, inflammatory, auto-immune, proliferative and hyper- proliferative diseases.
L'invention concerne un composé de la formule (I) où X représente O, S ou CH¿2?, R¿1? et R?2¿ représentent indépendamment l'un de l'autre hydrogène, alkyle C¿1-6? ou cycloalkyle C¿3-6? ou bien R?1¿ et R?2¿ forment, conjointement avec l'atome de carbone auquel ils sont liés, un groupe cycloalkyle C¿3-6?. Les composés de l'invention sont particulièrement adaptés à une utilisation dans le traitement ou la prévention de maladies allergiques, inflammatoires, auto-immunes, prolifératives et hyper-prolifératives.
Cheshire David
Cladingboel David
Cooper Martin
Hardern David
Hirst Simon
Astra Pharmaceuticals Ltd.
Fetherstonhaugh & Co.
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