Novel pyridonecarboxylic acid derivatives or salts thereof...

Details Novel pyridonecarboxylic acid derivatives or salts thereof... Novel pyridonecarboxylic acid derivatives or salts thereof...

C - Chemistry, Metallurgy

07

D

C07D 215/56 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) A61K 38/04 (2006.01) C07D 401/04 (2006.01) C07D 405/12 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 487/02 (2006.01) C07D 487/04 (2006.01) C07D 519/00 (2006.01) C07K 5/062 (2006.01) C07K 5/083 (2006.01)

Patent

CA 2211681

The invention provides a pyridonecarboxylic acid derivative of the following general formula (1): (see formula 1) wherein R1 is a hydrogen atom or carboxy protecting group, R2 is a nitro or substituted or unsubstituted amino group, R3 is a halogen atom, each of R4 and R5, which may be the same or different, is a hydrogen atom, halogen atom, lower alkyl group or lower alkoxy group, R6 is a hydrogen atom, halogen atom, hydroxy group, lower alkyl group or amino group, R7 is a hydrogen atom or halogen atom, A is a nitrogen atom or -CX= wherein X is a hydrogen atom, halogen atom, lower alkyl group or lower alkoxy group, and Z is a halogen atom or a saturated cyclic amino group which may have a substituent, or a salt thereof and an antibacterial agent comprising the same.

Dérivé d'acide pyridonecarboxylique représenté par la formule générale (1) ou un de ses sels et agent antibactérien contenant ledit dérivé, où R<1> représente hydrogène ou un groupe de protection carboxy; R<2> représente nitro ou amino éventuellement substitué; R<3> représente halogéno; R<4> et R<5> peuvent être similaires ou différents et chacun représente hydrogène, halogéno, alkyle inférieur ou alcoxy inférieur; R<6> représente hydrogène, halogeno, hydroxy, alkyle inférieur ou amino; R<7> représente hydrogène ou halogéno; A représente azote ou -CX= (où X représente hydrogène, halogéno, alkyle inférieur ou alcoxy inférieur); Z représente halogéno ou amino cyclique saturé éventuellement substitué.

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