Novel pyrimidine derivative

Details Novel pyrimidine derivative Novel pyrimidine derivative

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2283896

The present invention provides a novel pyrimidine derivative represented by general formula (1), wherein R, R4 and R8 are the same as defined in the specification, or pharmaceutically acceptable salt thereof, which possesses an excellent activity for inhibiting the formation of NO (nitrogen oxide) in vivo.

L'invention porte sur un nouveau dérivé de la pyrimidine de formule générale (1) dans laquelle: R, R?4¿ et R?8¿ sont identiques et définis dans la description, ou sur ses sels pharmacocompatibles, et qui possèdent une excellente activité inhibitrice de la formation in vivo de NO (oxyde d'azote).

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