Novel pyrimidine derivatives and their use in the treatment...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/49 (2006.01) A61K 31/505 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2760766

The invention concerns compounds of Formula (I): wherein L1, R1, R2, R3, R4 and X are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of disease, for example cancer.

L'invention porte sur des composés de formule (I) : dans laquelle L1, R1, R2, R3, R4 et X sont tels que définis dans la description. La présente invention porte également sur des procédés pour la préparation de tels composés, sur des compositions pharmaceutiques les contenant et sur leur utilisation dans le traitement d'une maladie, par exemple le cancer.

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