C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/04 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61P 3/06 (2006.01) C07D 207/30 (2006.01) C07D 207/325 (2006.01) C07D 207/33 (2006.01) C07D 207/333 (2006.01) C07D 207/335 (2006.01) C07D 207/36 (2006.01) C07D 207/48 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 407/04 (2006.01)
Patent
CA 2454863
The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel substituted pyrrole compounds of the general formula (I), their analogs, their derivatives, their polymorphs, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and their pharmaceutical compositions containing them. The invention also relates to the process for preparing such compounds, a composition containing such a compound and the use of such a compound and composition in medicine. The compounds lower triglyceride levels in blood and may be useful in the treatment of obesity, hyperlipidaemia, hypercholesteremia, syndrome X and diabetes.
L'invention concerne de nouveaux composés de pyrrole substitués, leurs dérivés, analogues, formes tautomères, stéréo-isomères, polymorphes, sels pharmaceutiquement acceptables, solvates pharmaceutiquement acceptables ainsi que des compositions pharmaceutiquement acceptables les contenant. Elle concerne notamment de nouveaux composés de pyrrole substitués représentés par la formule générale (I), leurs analogues, dérivés, polymorphes, formes tautomères, sels pharmaceutiquement acceptables, solvates pharmaceutiquement acceptables ainsi que des compositions pharmaceutiquement acceptables les contenant. Elle concerne également un procédé de préparation de ces composés, une composition contenant ce composé et l'utilisation du composé et de la composition en médecine. Ces composés permettent de réduire le taux sanguin de triglycérides et peuvent servir à traiter l'obésité, l'hyperlipidémie, l'hypercholestérolémie, le syndrome X et le diabète.
Barot Vijay Kumar
Basu Sujay
Lohray Braj Bhushan
Lohray Vidya Bhushan
Raval Preeti Saurin
Cadila Healthcare Limited
Smart & Biggar
LandOfFree
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