C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2721031
A novel co-crystal of N'-(7-fluoropyrrolo[1,2a]quinoxalin-4-yl)pyrazine-2- carbohydrazide with oxalic acid is disclosed. The disclosed oxalic acid co-crystal demonstrates cancer cell growth inhibition and is more bioavailable than the corre-sponding free base when administered as a suspension.
L'invention concerne un nouveau co-cristal de N'-(7-fluoropyrrolo[1,2a]quinoxalin-4-yl)pyrazine-2- carbohydrazide avec de l'acide oxalique. Le co-cristal d'acide oxalique décrit présente une inhibition de croissance de cellules de cancer et est plus biodisponible que la base libre correspondante lorsqu'il est administré sous la forme d'une suspension.
Bauer Victor J.
Jansen Burkhard
Kidon Barbara J.
O'neill Mike H.
Novelix Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
Novel (pyrroloquinoxalinyl) pyrazinecarbohydrazide-oxalic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel (pyrroloquinoxalinyl) pyrazinecarbohydrazide-oxalic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel (pyrroloquinoxalinyl) pyrazinecarbohydrazide-oxalic... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1982328