Novel pyruvate compounds and methods for use thereof

Details Novel pyruvate compounds and methods for use thereof Novel pyruvate compounds and methods for use thereof

A - Human Necessities

61

K

A61K 31/22 (2006.01) A01N 1/02 (2006.01) A23L 1/29 (2006.01) A61K 31/19 (2006.01) C07C 69/716 (2006.01) C07C 327/34 (2006.01)

Patent

CA 2249437

The invention comprises a novel pyruvate compound for the treatment or prevention of reperfusion injury following ischemia, diabetic effects, cholesterol levels, injured organs, ethanol intoxication, or as a foodstuff. The novel pyruvate compound is particularly a pyruvate thiolester, a glycerol- pyruvate ester or a dihydroxyacetone-pyruvate ester.

L'invention propose un nouveau composé de pyruvate destiné à être utilisé pour le traitement ou la prévention de la lésion de perfusion répétée à la suite d'une ischémie, des effets secondaires de la diabète, du niveau de cholestérol élevé, des blessures internes, de l'intoxication par l'éthanol ou en tant qu'aliment. Le nouveau composé de pyruvate est avant tout un thioester de pyruvate, un ester de glycérol-pyruvate ou un ester de dihydroxyacétone de-pyruvate.

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