C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/28 (2006.01) A61K 31/14 (2006.01) A61K 31/33 (2006.01) C07C 323/29 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01)
Patent
CA 2134229
ABSTRACT Quaternary ammonium salts represented by the following formula (I): Image (I) [wherein R1 and R2 represent lower alkyl groups which may be the same or different from each other; R3 represents hydrogen, lower alkyl, phenyl, benzyl, or -COOR4 (wherein R4 represents lower alkyl), A represents lower alkyl, lower alkenyl, lower alkynyl, -(CH2)p-COOR5 (wherein R5 represents hydrogen or lower alkyl, and p represents an integer of from 1 to 5), Image or Image (wherein R6 represents hydrogen, hydroxyl, nitro, lower alkyl, -COOR5, or -SO3R5); Q- represents a counter anion of quaternary ammonium salt; X represents Image , Image , Image or Image ; Y represents methylene, oxygen or sulfur; Z represents Image , Image , Image , Image , Image , Image , Image or Image (wherein R7 and R8 are the same or different from each other and independently represent hydrogen, halogen, nitro, lower alkyl or lower alkoxyl, and R9 represents lower alkyl or phenyl); 1 and m represent each an integer of 1 or 2; and n represents an integer of 1 to 3].
Ishii Katsuyuki
Kitagawa Osamu
Niwa Seiichi
Seiki Masao
Ueki Sigeru
Gowling Lafleur Henderson Llp
Zeria Pharmaceutical Co. Ltd.
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