Novel quinazoline derivatives

Details Novel quinazoline derivatives Novel quinazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 37/06 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2386163

Quinazoline derivatives represented by general formula (1) or pharmaceutically acceptable salts thereof in said formula R1 is nitro or halogeno; R2 and R4 are each hydrogen, C1-4 alkyl, carboxyl, or C2-5 alkoxycarbonyl; R3 is hydrogen, amino, optionally substituted C1-4 alkyl, C1-4 alkanoyl, or C2-5 alkoxycarbonyl; W is carbon or nitrogen; and m is 0 to 2.

L'invention concerne des dérivés de quinazoline de la formule générale (1) ou des sels pharmaceutiquement acceptables desdits dérivés. Dans ladite formule, R?1¿ est nitro ou halogéno; R?2¿ et R?4¿ sont chacun hydrogène, alkyle C¿1-4?, carboxyle, ou alcoxycarbonyle C¿2-5?, R?3¿ est hydrogène, amino, alkyle C¿1-4? éventuellement substitué, alcanoyle C¿1-4?, ou alcoxycarbonyle C¿2-5?; W est carbone ou azote; et m est compris entre 0 et 2.

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