Novel quinoxalinone derivatives

Details Novel quinoxalinone derivatives Novel quinoxalinone derivatives

C - Chemistry, Metallurgy

07

D

C07D 487/18 (2006.01) A61K 31/4995 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 498/18 (2006.01) C07D 498/22 (2006.01) C07D 515/18 (2006.01) C07D 515/22 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2503663

A quinoxalinone derivative of the formula (I): (see formula I) or a pharmaceutically acceptable salt or ester thereof, wherein; X is NH, S or the like; Y is O or the like; the partial structure (see formula II) is, for example, the formula: (see formula III) B1, B2, ......, Bn-1 and B n, (in which n is 4, 5 or 6) are each independently CH, N or the like; B'1, B'2, ......, B'n-1 and B'n (in which n is 4, 5 or 6) are each independently hydrogen or the like; and R is hydrogen, lower alkyl or the like.

L'invention concerne des dérivés de quinoxaline représentés par la formule générale (I) ou leurs sels ou esters pharmaceutiquement acceptables. Dans la formule générale (I), X représente NH, S ou équivalent ; Y représente O ou équivalent ; le groupe représenté par la formule générale (II·) représente notamment III où B¿1?, B¿2?, , B¿n-1? et B¿n? (n valant 4, 5 ou 6) représentent indépendamment CH, N ou équivalent ; et B'¿1?, B'¿2?, ., B'¿n-1?, et B'¿n? (n valant 4, 5 ou 6) représentent indépendamment de l'hydrogène ou équivalent ; et R représente hydrogène, alkyle bas ou équivalent.

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