Novel rat calcium channel subunits and related probes, cell...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2535921

Novel sequences for calcium channel .delta.28-2 and .delta.2 8-3 subunits are provided. Also provided are cell lines that express the novel calcium channel subunits of the invention. These cells may be used for identifying compounds capable of stimulating or inhibiting the activation of the calcium channels.

L'invention concerne de nouvelles séquences destinées aux sous-unités de canal calcique ?¿2?8-2 et ?¿2? 8-3. L'invention concerne également des lignées cellulaires exprimant les nouvelles sous-unités de canal calcique. Ces cellules peuvent être utilisées pour identifier des composés permettant de stimuler ou d'inhiber l'activation des canaux calciques.

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